SCHEMBL2802608

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6055199	0.93	PDE4D (0.62)	PDE4DPDE4APDE4BPDE4CPPARG
	SCHEMBL5492854	0.88	PDE4D (0.64)	PDE4DPDE4APDE4BPDE4CPPARG
	SCHEMBL15194927	0.86	PDE4D (0.47)	PDE4DPDE4APDE4BPDE4CHTR1A
	SCHEMBL10335590	0.86	PPARG (0.61)	PDE4DPDE4APDE4BPDE4CPPARG
	SCHEMBL28550136	0.86	CYP3A4 (0.67)	HTR1ACYP3A4TSHRNFKB1BLM
	SCHEMBL27107627	0.84	NR1I2 (0.50)	PDE4DPPARGPPARDPPARAHTR1A
	SCHEMBL27570423	0.83	PDE4D (0.48)	PDE4DPDE4APDE4BPDE4CPPARG
	SCHEMBL6055371	0.83	PPARG (0.61)	PDE4DPDE4APDE4BPDE4CPPARG
	SCHEMBL12898700	0.83	SLC2A1 (0.54)	PPARGPPARDPPARAHTR1AEPHX2
	SCHEMBL7465208	0.83	PPARG (0.43)	PDE4DPPARGPPARDPPARAHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.