Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 5/20 | 0.41 |
| ▸ | TDO2 | P48775 | 5/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6499230 | 0.89 | SRD5A2 (0.49) | SRD5A2IDO1TDO2SLC6A4F2 | |
| SCHEMBL7464307 | 0.85 | IDO1 (0.55) | SRD5A2IDO1TDO2SLC6A4PPARG | |
| SCHEMBL7355498 | 0.83 | SRD5A2 (0.41) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL27854181 | 0.82 | IDO1 (0.44) | SRD5A2IDO1TDO2SLC6A4MMP1 | |
| SCHEMBL7455793 | 0.82 | SRD5A2 (0.39) | SRD5A2IDO1TDO2SLC6A4MMP1 | |
| SCHEMBL5535686 | 0.75 | PPARA (0.40) | IDO1TDO2SLC6A4ALDH1A1SMN1; SMN2 | |
| SCHEMBL7466004 | 0.75 | IDO1 (0.40) | IDO1TDO2SLC6A4SLC6A3 | |
| SCHEMBL9859672 | 0.74 | SRD5A2 (0.57) | SRD5A2IDO1TDO2SLC6A4F2 | |
| SCHEMBL2086755 | 0.74 | PBRM1 (0.33) | SRD5A2SLC6A4F2ADRA2AADRA2B | |
| SCHEMBL824952 | 0.71 | SRD5A2 (0.55) | SRD5A2IDO1TDO2SLC6A4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |