Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 5/20 | 0.40 |
| ▸ | TDO2 | P48775 | 5/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471512 | 0.89 | SRD5A2 (0.36) | IDO1TDO2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7462989 | 0.86 | IDO1 (0.54) | IDO1TDO2SLC6A4 | |
| SCHEMBL7461974 | 0.83 | IDO1 (0.51) | IDO1TDO2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7466815 | 0.83 | MEN1 (0.37) | IDO1TDO2SLC6A4SLC6A3 | |
| SCHEMBL7471840 | 0.83 | ACP3 (0.42) | IDO1TDO2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL7468229 | 0.81 | ACP3 (0.44) | — | |
| SCHEMBL7460305 | 0.81 | IDO1 (0.53) | IDO1TDO2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL14648029 | 0.80 | SLC6A4 (0.34) | IDO1TDO2SLC6A4SLC6A2 | |
| SCHEMBL7466003 | 0.80 | OPRD1 (0.39) | — | |
| SCHEMBL7462087 | 0.76 | IDO1 (0.36) | IDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |