Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.55 |
| ▸ | TDO2 | P48775 | 3/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465279 | 0.85 | SRD5A2 (0.41) | IDO1TDO2SLC6A4SRD5A2PPARG | |
| SCHEMBL6499230 | 0.85 | SRD5A2 (0.49) | IDO1TDO2SLC6A4SRD5A2 | |
| SCHEMBL7460123 | 0.84 | IDO1 (0.51) | IDO1TDO2SLC6A4SRD5A2CNR2 | |
| SCHEMBL5542031 | 0.79 | HTR6 (0.42) | IDO1TDO2SLC6A4MEN1KMT2A | |
| SCHEMBL7462989 | 0.77 | IDO1 (0.54) | IDO1TDO2SLC6A4CNR2 | |
| SCHEMBL17515003 | 0.76 | IDO1 (0.36) | IDO1TDO2SLC6A4CNR2SLC7A5 | |
| SCHEMBL7355498 | 0.76 | SRD5A2 (0.41) | SRD5A2CNR2MEN1KMT2APPARG | |
| SCHEMBL9859672 | 0.71 | SRD5A2 (0.57) | IDO1TDO2SLC6A4SRD5A2 | |
| SCHEMBL2086755 | 0.71 | PBRM1 (0.33) | SLC6A4SRD5A2 | |
| SCHEMBL17319365 | 0.70 | SLC6A4 (0.49) | IDO1TDO2SLC6A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | disclosed |