Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 3/20 | 0.37 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.37 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.37 |
| ▸ | IDO1 | P14902 | 8/20 | 0.35 |
| ▸ | TDO2 | P48775 | 8/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | IDO2 | Q6ZQW0 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7355498 | 0.89 | SRD5A2 (0.41) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL7465279 | 0.89 | SRD5A2 (0.41) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL7464307 | 0.85 | IDO1 (0.55) | SRD5A2IDO1TDO2SLC6A4 | |
| SCHEMBL9859672 | 0.84 | SRD5A2 (0.57) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL864142 | 0.79 | FFAR1 (0.49) | ADRA2AADRA2BADRA2CSCN3AKCNH2 | |
| SCHEMBL11462370 | 0.79 | DPP4 (0.39) | F2ADRA2AADRA2CSLC6A4LMNA | |
| SCHEMBL7959775 | 0.79 | TSHR (0.38) | SRD5A2ADRA2AADRA2CSLC6A4LMNA | |
| SCHEMBL875512 | 0.79 | TSHR (0.39) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL2086755 | 0.79 | PBRM1 (0.33) | SRD5A2F2ADRA2AADRA2BADRA2C | |
| SCHEMBL10497077 | 0.79 | TRPA1 (0.38) | SRD5A2F2ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114213433-B | Process for the preparation of C-3 tetrahydrofuran substituted cephalosporin-siderophore conjugates | 重庆医药高等专科学校 | 2023-03-24 | — | — | CN | disclosed |
| CN-114213433-A | Process for the preparation of C-3 tetrahydrofuran substituted cephalosporin-siderophore conjugates | 重庆医药高等专科学校 | 2022-03-22 | — | — | CN | disclosed |
| CN-111620893-B | C-3 tetrahydrofuran substituted cephalosporin-siderophore coupling compound and preparation method and application thereof | 重庆医药高等专科学校 | 2021-12-14 | — | — | CN | disclosed |
| CN-111620893-A | C-3 tetrahydrofuran substituted cephalosporin-siderophore coupling compound and preparation method and application thereof | 重庆医药高等专科学校 | 2020-09-04 | — | — | CN | disclosed |
| US-6908996-B2 | Compounds and method for preparing 3-methylcephams | IMPERIAL COLLEGE OF LONDON (GB) | 2005-06-21 | — | — | US | disclosed |
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | COOPER CONSULTING | 2004-06-03 | — | — | US | disclosed |
| US-6683176-B2 | FOR USE IN PRODUCING AMINO ACID DERIVATIVE ANTIBIOTICS | COOPER CONSULTING | 2004-01-27 | — | — | US | disclosed |
| EP-1183262-A4 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | COOPER CONSULTING INC (US) | 2003-04-09 | — | — | EP | disclosed |
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | disclosed |
| EP-1183262-A1 | INTERMEDIATES FOR AND SYNTHESIS OF 3-METHYLENE CEPHAMS | Cooper Consulting Inc. (US) | 2002-03-06 | — | — | EP | disclosed |
| US-4375475-A | ANTICHOLESTEROL AGENTS | MERCK & CO., INC. (US) | 1983-03-01 | — | — | US | disclosed |
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |
| US-4176231-A | Process for preparing 3-exomethylenecepham sulfoxides | LILLY INDUSTRIES LIMITED (GB) | 1979-11-27 | — | — | US | disclosed |
| US-4159266-A | AZETIDINONE SULFINIC ACID DERIVATIVES | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-4052387-A | METHOD OF PREPARATION OF 3-METHYLENECEPHAMS | ELI LILLY AND COMPANY (US) | 1977-10-04 | — | — | US | disclosed |
| US-4048160-A | Process for preparation of 7-alkoxy-3-bromomethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4048163-A | Process for preparation of 7-alkoxy-3-chloromethylcephems | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |
| US-4038275-A | PROCESS FOR PREPARATION OF 3-HYDROXYMETHYLCEPHEMS | ELI LILLY AND COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040106790-A1 | Novel compounds and method for preparing 3-methylcephams | DHPS, FDPS, COASY | SRD5A2 174/4885F2 2745/4885ADRA2A 4446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.