Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.45 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7467775 | 0.78 | ANPEP (0.47) | ERAP1ANPEPERAP2GRIK1KIF11 | |
| SCHEMBL7476688 | 0.76 | ANPEP (0.46) | ERAP1ANPEPERAP2GRIK1KIF11 | |
| SCHEMBL7469819 | 0.74 | NPC1 (0.50) | ERAP1ANPEPERAP2METAP2METAP1 | |
| SCHEMBL14562912 | 0.70 | ERAP1 (0.46) | CES1ERAP1ANPEPERAP2GRIK1 | |
| SCHEMBL8018220 | 0.69 | ERAP1 (0.53) | ERAP1ANPEPERAP2GRIK1METAP2 | |
| SCHEMBL8409870 | 0.69 | ANPEP (0.49) | ERAP1ANPEPERAP2GRIK1METAP2 | |
| Trifluoroacetic Acid SCHEMBL8142317 | 0.69 | CPA1 (0.49) | CES1FAAHCNR2TSHR | |
| Trifluoroacetic Acid SCHEMBL9943876 | 0.69 | SLC15A1 (0.51) | CES1ERAP1ANPEPERAP2FAAH | |
| Trifluoroacetic Acid SCHEMBL7023585 | 0.69 | LTA4H (0.47) | ERAP1ERAP2METAP2METAP1TSHR | |
| Trifluoroacetic Acid SCHEMBL9102768 | 0.69 | SLC15A1 (0.51) | CES1ERAP1ANPEPERAP2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287605-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1988-10-26 | — | — | EP | claimed |
| WO-1988002363-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1988-04-07 | — | — | WO | claimed |