Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.47 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | METAP2 | P50579 | 2/20 | 0.42 |
| ▸ | METAP1 | P53582 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7476688 | 0.79 | ANPEP (0.46) | ANPEPERAP1ERAP2HPGDMEN1 | |
| SCHEMBL7465282 | 0.78 | CES1 (0.46) | ANPEPERAP1ERAP2METAP2METAP1 | |
| SCHEMBL7469819 | 0.76 | NPC1 (0.50) | ANPEPERAP1ERAP2MEN1HTT | |
| Hydrochloric Acid SCHEMBL1130842 | 0.72 | ANPEP (0.50) | ANPEPERAP1ERAP2HPGDMEN1 | |
| SCHEMBL11827382 | 0.72 | MMP12 (0.50) | HTTTSHR | |
| SCHEMBL6576344 | 0.71 | CYP1A2 (0.44) | ANPEPERAP1ERAP2HPGDMEN1 | |
| SCHEMBL6576342 | 0.71 | CYP1A2 (0.44) | ANPEPERAP1ERAP2HPGDMEN1 | |
| Homophenylalanine SCHEMBL1078733 | 0.71 | ALPI (0.64) | ANPEPERAP1ERAP2GRIK1KIF11 | |
| Homophenylalanine SCHEMBL44312 | 0.71 | ALPI (0.64) | ANPEPERAP1ERAP2GRIK1KIF11 | |
| Homophenylalanine SCHEMBL130567 | 0.71 | ALPI (0.64) | ANPEPERAP1ERAP2GRIK1KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0287605-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 1988-10-26 | — | — | EP | disclosed |
| WO-1988002363-A1 | AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) | 1988-04-07 | — | — | WO | disclosed |