Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7463453 | 0.81 | HSD17B10 (0.48) | MEN1KMT2AMAPK1HSD17B10TP53 | |
| SCHEMBL7478261 | 0.77 | L3MBTL1 (0.44) | MEN1KMT2AMAPK1HSD17B10TP53 | |
| SCHEMBL7465305 | 0.75 | BRD4 (0.31) | BRD4 | |
| SCHEMBL7472416 | 0.73 | PARP1 (0.48) | MEN1KMT2AMAPK1HSD17B10TP53 | |
| SCHEMBL7468823 | 0.73 | BRD4 (0.45) | MEN1KMT2ABRD4HSD17B10 | |
| SCHEMBL7470585 | 0.73 | USP2 (0.56) | MEN1KMT2AHSD17B10 | |
| SCHEMBL7468480 | 0.72 | BRD4 (0.42) | MEN1KMT2AMAPK1BRD4TP53 | |
| SCHEMBL5802317 | 0.72 | L3MBTL1 (0.43) | MEN1KMT2ADUTMAPK1BRD4 | |
| SCHEMBL7472662 | 0.72 | L3MBTL1 (0.43) | MEN1KMT2AMAPK1BRD4HSD17B10 | |
| SCHEMBL7465311 | 0.72 | HSD17B10 (0.31) | HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869949-B1 | BENZOXAZINE ANTIMICROBIAL AGENTS | ORTHO MCNEIL PHARM INC (US) | 2002-12-18 | — | — | EP | disclosed |
| US-5854242-A | Benzoxazine antimicrobial agents | ORTHO PHARMACEUTICAL CORPORATION (US) | 1998-12-29 | — | — | US | disclosed |
| US-5696117-A | BACTERICIDE | ORTHO PHARMACEUTICAL CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |