Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469954 | 0.88 | PDGFRB (0.44) | MAPTACHEBACE1ALDH1A1GAA | |
| SCHEMBL7470741 | 0.84 | MAPT (0.42) | MAPTACHEBACE1ALDH1A1GAA | |
| SCHEMBL7473072 | 0.83 | MAPT (0.39) | MAPTACHEBACE1ALDH1A1GAA | |
| SCHEMBL7460778 | 0.83 | ACHE (0.51) | MAPTACHEBACE1ALDH1A1ATM | |
| SCHEMBL7465661 | 0.81 | ACHE (0.45) | MAPTACHEBACE1ALDH1A1GAA | |
| SCHEMBL27911852 | 0.77 | HTT (0.47) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP3A4 | |
| SCHEMBL7464038 | 0.77 | ACHE (0.55) | MAPTACHEBACE1ALDH1A1LMNA | |
| SCHEMBL7475891 | 0.74 | ACHE (0.54) | MAPTACHEBACE1ALDH1A1LMNA | |
| SCHEMBL7469778 | 0.73 | MAPT (0.45) | MAPTACHEBACE1ALDH1A1GAA | |
| SCHEMBL7476091 | 0.73 | ACHE (0.54) | MAPTACHEBACE1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |