Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.45 |
| ▸ | BACE1 | P56817 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.37 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470741 | 0.90 | MAPT (0.42) | ACHEBACE1USP2CYP1A2CYP3A4 | |
| SCHEMBL7473072 | 0.89 | MAPT (0.39) | ACHEBACE1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7462862 | 0.88 | PDGFRB (0.44) | ACHEBACE1USP2CYP1A2CYP3A4 | |
| SCHEMBL7460778 | 0.85 | ACHE (0.51) | ACHEBACE1USP2CYP1A2CYP3A4 | |
| SCHEMBL7465361 | 0.81 | MAPT (0.43) | ACHEBACE1USP2CYP1A2CYP3A4 | |
| SCHEMBL7468805 | 0.78 | ALDH1A1 (0.54) | ACHEBACE1ALDH1A1MAPTGAA | |
| SCHEMBL7465618 | 0.78 | PDGFRB (0.42) | ACHEBACE1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7468815 | 0.77 | ACHE (0.51) | ACHEBACE1USP2CYP1A2CYP3A4 | |
| SCHEMBL7476089 | 0.77 | PDGFRB (0.41) | ACHEBACE1CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL7459198 | 0.75 | MEN1 (0.53) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |