Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 5/20 | 0.54 |
| ▸ | BACE1 | P56817 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | AURKA | O14965 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7464038 | 0.88 | ACHE (0.55) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL7473621 | 0.84 | PDGFRB (0.60) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL7475884 | 0.83 | ALDH1A1 (0.54) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL7468677 | 0.83 | ALDH1A1 (0.54) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL7458931 | 0.83 | NSD2 (0.56) | LMNAMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL7475891 | 0.82 | ACHE (0.54) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL9224976 | 0.80 | PDGFRB (0.64) | ACHEBACE1LMNAMAPTPDGFRB | |
| SCHEMBL7468826 | 0.79 | EGFR (0.56) | LMNAMAPTKDM4EALDH1A1HTT | |
| SCHEMBL7462130 | 0.79 | MAPT (0.42) | ACHEBACE1LMNAMAPTAURKA | |
| SCHEMBL7469735 | 0.78 | LMNA (0.47) | ACHEBACE1LMNAMAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1229025-A1 | NOVEL QUINAZOLINE DERIVATIVES | Japan Energy Corporation (JP) | 2002-08-07 | — | — | EP | disclosed |