Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1009189 | 0.92 | NSD2 (0.45) | RAB9AMAOBNSD2ABCB1CHRNB2 | |
| SCHEMBL6424007 | 0.87 | NSD2 (0.43) | MAOBNSD2ABCB1EPHX2POLB | |
| SCHEMBL7233237 | 0.80 | NSD2 (0.53) | TSHRRAB9ANSD2EPHX2POLB | |
| SCHEMBL1009190 | 0.77 | NSD2 (0.42) | RAB9AMAOBNSD2GPR119ABCB1 | |
| SCHEMBL7204913 | 0.76 | MLYCD (0.36) | MAOBNSD2ABCB1CHRNB2CHRNB4 | |
| SCHEMBL1010216 | 0.76 | MEP1A (0.50) | MAOBABCB1 | |
| SCHEMBL2578969 | 0.76 | NSD2 (0.41) | TSHRMAOBNSD2CHRNB2CHRNB4 | |
| SCHEMBL30577123 | 0.75 | SSTR4 (0.47) | NSD2GPR119EPHX2POLB | |
| SCHEMBL407573 | 0.75 | ABCB1 (0.44) | NSD2GPR119ABCB1EPHX2POLB | |
| SCHEMBL4662657 | 0.75 | HDAC3 (0.46) | TSHRRAB9ANSD2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032574-A1 | NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-06-08 | — | — | WO | disclosed |