SCHEMBL7465459

SCHEMBL7465459

O=C(O)OC(CO)c1cccc(Cl)c1

nearest known ligand 0.49

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
IDO1 P14902 2/20 0.45
ACP3 P15309 1/20 0.45
AOC3 Q16853 1/20 0.44
HPGD P15428 2/20 0.40
ALDH1A1 P00352 1/20 0.40
SLC6A4 P31645 1/20 0.40
CACNA1G O43497 1/20 0.40
CACNA2D1 P54289 1/20 0.40
CACNA1B Q00975 1/20 0.40
CACNB1 Q02641 1/20 0.40
CACNA1C Q13936 1/20 0.40
CASR P41180 1/20 0.40
TDO2 P48775 1/20 0.39
GSR P00390 1/20 0.39
ALOX15 P16050 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28622675 0.85 AOC3 (0.47) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL28622677 0.85 AOC3 (0.47) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL2836232 0.82 GSR (0.55) KMT2AGSR
SCHEMBL28076433 0.78 MAPT (0.46) MEN1KMT2AIDO1AOC3HPGD
SCHEMBL24615882 0.77 AOC3 (0.64) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL9516619 0.75 AOC3 (0.47) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL8771150 0.75 FFAR1 (0.47) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL28040166 0.74 AOC3 (0.46) MEN1KMT2AIDO1ACP3AOC3
SCHEMBL10775144 0.74 ACP3 (0.52) MEN1KMT2AACP3AOC3HPGD
SCHEMBL6366834 0.74 MEN1 (0.67) MEN1KMT2AACP3HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0907635-B1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK CORP (KR) 2002-09-25 EP disclosed
US-20010034365-A1 Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol CHOI YONG MOON (US) 2001-10-25 US disclosed
US-6127412-A TREATMENT OF DISORDERS OF THE CENTRAL NERVOUS SYSTEM, ESPECIALLY AS ANTICONVULSANTS, ANTIEPILEPTIC AND NEUROPROTECTIVE AGENTS AND CENTRALLY ACTING MUSCLE RELAXANTS SK CORPORATION (US) 2000-10-03 US disclosed
US-6103759-A COMPRISING PURE ENANTIOMERIC FORMS, AS WELL AS ENANTIOMERIC MIXTURES, OF (2-(2-CHLOROPHENYL)-2-HYDROXYETHYL)OXYCARBOXAMIDE; USEFUL FOR TRATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS SK CORPORATION (US) 2000-08-15 US disclosed
EP-0907635-A1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK Corporation (KR) 1999-04-14 EP disclosed
US-5854283-A Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol YUKONG LIMITED (KR) 1998-12-29 US disclosed
WO-1997026241-A1 HALOGEN SUBSTITUTED CARBAMATE COMPOUNDS FROM 2-PHENYL-1,2-ETHANEDIOL SK CORPORATION (KR) 1997-07-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010034365-A1 Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol DDT, GRIK2, GABRD MEN1 1115/4885KMT2A 471/4885IDO1 2364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.