SCHEMBL2836232

SCHEMBL2836232

O=C(O)OC(CO)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.55
BLM P54132 1/20 0.46
CYP2D6 P10635 2/20 0.41
SRC P12931 1/20 0.41
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
MAPK1 P28482 1/20 0.40
PABPC1 P11940 1/20 0.40
APOBEC3A P31941 1/20 0.40
APOBEC3G Q9HC16 1/20 0.40
KMT2A Q03164 1/20 0.39
CES2 O00748 1/20 0.39
CES1 P23141 1/20 0.39
TRPA1 O75762 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8467351 0.84 PABPC1 (0.55) GSRBLMPABPC1APOBEC3AAPOBEC3G
SCHEMBL28500481 0.84 GSR (0.51) GSRCYP2D6LMNACYP1A2PKM
SCHEMBL6330737 0.84 GSR (0.51) GSRCYP2D6LMNACYP1A2PKM
SCHEMBL1043546 0.84 GSR (0.51) GSRCYP2D6LMNACYP1A2PKM
SCHEMBL28092954 0.82 GSR (0.50) GSRBLMCYP2D6SRCLMNA
SCHEMBL4957988 0.82 TSHR (0.53) GSRBLMLMNAMAPK1KMT2A
SCHEMBL7465459 0.82 MEN1 (0.47) GSRKMT2A
SCHEMBL2944469 0.82 GABBR2 (0.48) GSRCYP2D6SRCCYP1A2PKM
SCHEMBL11845837 0.82 EPHX1 (0.52) CYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL648756 0.82 LMNA (0.47) GSRCYP2D6LMNAPABPC1APOBEC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9263630-A None JP disclosed
EP-2248799-B1 PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL)-2-HYDROXY-ETHYL CARBAMATES SK BIOPHARMACEUTICALS CO LTD (KR) 2015-05-20 EP disclosed
EP-2248799-A1 Process for preparing 2-(substituted phenyl)-2-hydroxy-ethyl carbamates Ortho-McNeil Pharmaceutical, Inc. (US) 2010-11-10 EP disclosed
EP-1461309-A1 PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL) - 2 - HYDROXY-ETHYL CARBAMATES Ortho-McNeil Pharmaceutical, Inc. (US) 2004-09-29 EP disclosed
WO-2003053916-A1 PROCESS FOR PREPARING 2-(SUBSTITUTED PHENYL) - 2 - HYDROXY-ETHYL CARBAMATES ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) 2003-07-03 WO disclosed
JP-H09263630-A MODIFIED POLYCARBONATE BAYER AG 1997-10-07 JP disclosed