Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.52 |
| ▸ | F10 | P00742 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 2/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.40 |
| ▸ | C1S | P09871 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.39 |
| ▸ | ABAT | P80404 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3191980 | 0.75 | LOXL2 (0.48) | LOXL2F10HDAC3HDAC6NCOR2 | |
| SCHEMBL27468701 | 0.75 | CYP1A2 (0.46) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL38758 | 0.73 | ALDH1A1 (0.60) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL9344424 | 0.73 | ALDH1A1 (0.60) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Bicarbonate SCHEMBL31055587 | 0.72 | ABAT (0.60) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL1567841 | 0.71 | ALDH1A1 (0.58) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL7428232 | 0.71 | ALDH1A1 (0.58) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL1206230 | 0.71 | ALDH1A1 (0.58) | LOXL2F10HDAC3HDAC6NCOR2 | |
| SCHEMBL4603744 | 0.71 | LOXL2 (0.58) | LOXL2F10HDAC3HDAC6NCOR2 | |
| Aminomethylbenzoic Acid SCHEMBL28342619 | 0.71 | ALDH1A1 (0.58) | LOXL2F10HDAC3HDAC6NCOR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000032574-A1 | NOVEL 2-PYRIDONE DERIVATIVES, PREPARATION METHOD AND THERAPEUTIC USE | SANOFI-SYNTHELABO (FR) | 2000-06-08 | — | — | WO | disclosed |