Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABAT | P80404 | 1/20 | 0.60 |
| ▸ | LOXL2 | Q9Y4K0 | 6/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.58 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | F11 | P03951 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycine SCHEMBL2596528 | 0.88 | GLRA1 (0.56) | ABATLOXL2HRH3TPSAB1HDAC3 | |
| Benzylamine SCHEMBL2841170 | 0.88 | LOXL2 (0.78) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Benzylamine SCHEMBL2841167 | 0.88 | LOXL2 (0.78) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Benzylamine SCHEMBL25352130 | 0.86 | LOXL2 (0.74) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Benzylamine SCHEMBL9567530 | 0.86 | LOXL2 (0.74) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Bicarbonate SCHEMBL31055574 | 0.84 | LOXL2 (0.62) | LOXL2SMN1; SMN2TAAR1CYP1A2CYP2D6 | |
| SCHEMBL933080 | 0.84 | CA2 (0.62) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Aminomethylbenzoic Acid SCHEMBL38758 | 0.84 | ALDH1A1 (0.60) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Aminomethylbenzoic Acid SCHEMBL9344424 | 0.84 | ALDH1A1 (0.60) | ABATLOXL2TPSAB1HDAC3HDAC6 | |
| Benzene SCHEMBL734439 | 0.83 | LOXL2 (0.80) | ABATLOXL2HRH3TAAR1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118302406-A | Process for preparing diisocyanates | 韩华思路信(株) | 2024-07-05 | — | — | CN | claimed |
| CN-119907820-A | Isocyanate composition | 韩华思路信(株) | 2025-04-29 | — | — | CN | disclosed |
| CN-118302406-A | Process for preparing diisocyanates | 韩华思路信(株) | 2024-07-05 | — | — | CN | disclosed |