Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.34 |
| ▸ | CCR1 | P32246 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.31 |
| ▸ | ESRRB | O95718 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468456 | 0.89 | CCR3 (0.35) | CCR3CCR1POLBL3MBTL1CNR2 | |
| SCHEMBL7455821 | 0.89 | KDM1A (0.35) | LMNACNR2TDP1 | |
| SCHEMBL7467499 | 0.83 | CCR6 (0.41) | CCR3CCR1LMNAL3MBTL1 | |
| SCHEMBL7460719 | 0.81 | MCHR1 (0.53) | KCNA3DRD2 | |
| SCHEMBL7463866 | 0.80 | MT-CO2 (0.33) | CCR3CCR1POLBL3MBTL1CNR2 | |
| SCHEMBL7465038 | 0.80 | KDM1A (0.34) | LMNACNR2 | |
| SCHEMBL7463862 | 0.78 | MCHR1 (0.42) | CCR3CCR1CNR2KCNA3DRD4 | |
| SCHEMBL7462484 | 0.76 | CCR6 (0.40) | LMNAKMT2AL3MBTL1TDP1 | |
| SCHEMBL7466666 | 0.76 | MCHR1 (0.47) | CCR3DRD2OPRM1 | |
| SCHEMBL7463962 | 0.76 | MCHR1 (0.47) | CCR3CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |