Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCR3 | P51677 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462484 | 0.93 | CCR6 (0.40) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| SCHEMBL7464946 | 0.90 | MCHR1 (0.39) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| SCHEMBL7465122 | 0.88 | CCR6 (0.37) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| Hydrochloric Acid SCHEMBL7460657 | 0.85 | SIGMAR1 (0.39) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| Hydrochloric Acid SCHEMBL7461937 | 0.85 | HTR7 (0.39) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| Hydrochloric Acid SCHEMBL7463934 | 0.84 | MCHR1 (0.45) | CCR6PAX8MCHR1CHRM2CHRM5 | |
| Hydrochloric Acid SCHEMBL7458660 | 0.84 | MCHR1 (0.51) | MCHR1CHRM2CHRM5CHRM1CHRM3 | |
| SCHEMBL7465609 | 0.83 | CCR3 (0.34) | LMNACCR3CCR1L3MBTL1 | |
| SCHEMBL7463105 | 0.81 | MCHR1 (0.65) | MCHR1CCR3SIGMAR1CCR1 | |
| SCHEMBL7466059 | 0.81 | LMNA (0.40) | MCHR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |