Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.30 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465674 | 1.00 | LMNA (0.33) | LMNASMN1; SMN2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL1496401 | 0.83 | ALDH1A1 (0.34) | LMNASMN1; SMN2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL13049755 | 0.83 | ALDH1A1 (0.34) | LMNASMN1; SMN2ALDH1A1CYP2D6CYP2C19 | |
| SCHEMBL23201575 | 0.76 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL7458559 | 0.76 | LMNA (0.36) | LMNACYP2D6CYP2C19 | |
| SCHEMBL7458566 | 0.76 | LMNA (0.36) | LMNACYP2D6CYP2C19 | |
| SCHEMBL15526954 | 0.76 | SMN1; SMN2 (0.33) | LMNASMN1; SMN2ALDH1A1TSHRCYP2D6 | |
| SCHEMBL14389451 | 0.75 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL8752641 | 0.75 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2ALDH1A1TSHRGAA | |
| SCHEMBL9717667 | 0.75 | SMN1; SMN2 (0.48) | LMNASMN1; SMN2ALDH1A1TSHRGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0930292-B1 | PROCESS FOR PREPARING BETA-AMINO-ALPHA-HYDROXY ACID DERIVATIVES | KANEKA CORP (JP) | 2002-10-16 | — | — | EP | disclosed |
| US-6087530-A | Process for preparing β-amino-α-hydroxy acid derivatives | KANEKA CORPORATION (JP) | 2000-07-11 | — | — | US | disclosed |
| EP-0930292-A1 | PROCESS FOR PREPARING $g(b)-AMINO-$g(a)-HYDROXY ACID DERIVATIVES | KANEKA CORPORATION (JP) | 1999-07-21 | — | — | EP | disclosed |