Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MCHR1 | Q99705 | 6/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | BLK | P51451 | 1/20 | 0.30 |
| ▸ | BMX | P51813 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454228 | 0.89 | MAOB (0.43) | MAOAMAOBMCHR1MAPTHTR2C | |
| SCHEMBL7459577 | 0.89 | MAOA (0.39) | MAOAMAOBMCHR1 | |
| SCHEMBL7463814 | 0.88 | PPARG (0.35) | MAOAMAOBMCHR1HTR2C | |
| SCHEMBL7458493 | 0.86 | HTR2C (0.39) | MAOAMAOBMCHR1HTR2C | |
| SCHEMBL7457048 | 0.86 | MAOB (0.42) | MAOAMAOB | |
| SCHEMBL7466444 | 0.83 | HTR2C (0.40) | MCHR1HTR2C | |
| SCHEMBL7457982 | 0.82 | MCHR1 (0.30) | MCHR1 | |
| SCHEMBL7454776 | 0.80 | MCHR1 (0.31) | MCHR1 | |
| SCHEMBL7465593 | 0.80 | — | — | |
| SCHEMBL7465859 | 0.80 | MEN1 (0.30) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |