Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 13/20 | 0.42 |
| ▸ | MAOA | P21397 | 4/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454228 | 0.88 | MAOB (0.43) | MAOBMAOAALDH1A1PPARG | |
| SCHEMBL7463814 | 0.87 | PPARG (0.35) | MAOBMAOAPPARG | |
| SCHEMBL7465742 | 0.86 | APP (0.33) | MAOBMAOA | |
| SCHEMBL7461933 | 0.83 | MAPT (0.34) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL7457982 | 0.81 | MCHR1 (0.30) | — | |
| SCHEMBL7466444 | 0.80 | HTR2C (0.40) | — | |
| SCHEMBL7460879 | 0.80 | PKM (0.34) | — | |
| SCHEMBL7465859 | 0.79 | MEN1 (0.30) | ALDH1A1 | |
| SCHEMBL7455042 | 0.79 | BCAT2 (0.38) | SMN1; SMN2NPC1RAB9AALDH1A1PPARG | |
| SCHEMBL6771342 | 0.79 | ALDH1A1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |