Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7459566 | 0.90 | PTGDR2 (0.38) | PPARDPPARARORCPKMPTGDR2 | |
| SCHEMBL7455671 | 0.88 | PTGDR2 (0.37) | PPARDPPARAPKMPTGDR2MEN1 | |
| SCHEMBL7456814 | 0.88 | PPARD (0.36) | PPARDPPARARORCPKMMEN1 | |
| SCHEMBL7457701 | 0.88 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL7454792 | 0.86 | PKM (0.34) | PPARDPPARARORCPKMPTGDR2 | |
| SCHEMBL7467239 | 0.85 | PTGDR2 (0.34) | PPARDPPARARORCPTGDR2PPARG | |
| SCHEMBL7051566 | 0.82 | KDM4E (0.35) | MEN1KMT2APOLB | |
| SCHEMBL7459571 | 0.82 | AGER (0.35) | PPARDPPARAPKMMEN1MAPT | |
| SCHEMBL7454798 | 0.82 | PPARD (0.35) | PPARDPPARAPKMMEN1MAPT | |
| SCHEMBL7464757 | 0.81 | PPARD (0.36) | PPARDPPARARORCPKMMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0908457-B1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | BASF AG (DE) | 2002-11-13 | — | — | EP | disclosed |
| EP-0908457-A1 | 3-(1,2-benzisothiazol- and isoxazol-5-Y1)-2,4(1H,3H)-pyrimidinedione or thione and 3-(1,2-benzisothiazol- and isoxazol-5-y1)-4(3H)-pyrimidinone or thione herbicidal agents | American Cyanamid Company (US) | 1999-04-14 | — | — | EP | disclosed |