Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.39 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466052 | 0.95 | MCHR1 (0.56) | MCHR1LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL31122455 | 0.81 | P2RX7 (0.45) | LMNAMAPTCA1CA2P2RX7 | |
| SCHEMBL7462473 | 0.79 | MCHR1 (0.62) | MCHR1LMNAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL6924285 | 0.79 | LMNA (0.59) | LMNAMAPTCA1CA2P2RX7 | |
| SCHEMBL7465787 | 0.78 | LMNA (0.41) | LMNAMAPTCA1CA2P2RX7 | |
| SCHEMBL7465108 | 0.78 | MCHR1 (0.61) | MCHR1LMNAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL7467488 | 0.77 | MCHR1 (0.65) | MCHR1LMNAMAPK1ALDH1A1NPSR1 | |
| SCHEMBL6245784 | 0.77 | HTT (0.54) | LMNAALDH1A1MAPTCA1CA2 | |
| SCHEMBL7464939 | 0.76 | MCHR1 (0.64) | MCHR1LMNAMAPK1ALDH1A1MAPT | |
| SCHEMBL8312617 | 0.76 | CYP24A1 (0.37) | ALDH1A1CA1CA2SMN1; SMN2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |