Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | F13A1 | P00488 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 1/20 | 0.34 |
| ▸ | TGM1 | P22735 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466059 | 0.95 | LMNA (0.40) | LMNAMAPTCA1CA2P2RX7 | |
| SCHEMBL7462484 | 0.81 | CCR6 (0.40) | LMNAKMT2ACCR5 | |
| SCHEMBL7465122 | 0.80 | CCR6 (0.37) | LMNAKMT2ACCR5 | |
| SCHEMBL7467499 | 0.79 | CCR6 (0.41) | LMNA | |
| SCHEMBL7465776 | 0.78 | MCHR1 (0.53) | LMNAMAPTCA1CA2P2RX7 | |
| SCHEMBL7464946 | 0.78 | MCHR1 (0.39) | LMNAKMT2ACCR5 | |
| SCHEMBL8312617 | 0.76 | CYP24A1 (0.37) | CA1CA2KMT2AGAAPKM | |
| Hydrochloric Acid SCHEMBL7461937 | 0.75 | HTR7 (0.39) | — | |
| Hydrochloric Acid SCHEMBL7460657 | 0.75 | SIGMAR1 (0.39) | — | |
| SCHEMBL7462760 | 0.74 | ENPP3 (0.34) | LMNAMAPTKMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219294-A1 | MELANIN CONCENTRATING HORMONE ANTAGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |