Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 17/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465823 | 0.91 | ELANE (0.59) | ELANERAB9A | |
| SCHEMBL7018684 | 0.72 | ELANE (0.62) | ELANE | |
| SCHEMBL8521554 | 0.71 | ELANE (0.60) | ELANE | |
| SCHEMBL7310086 | 0.71 | ELANE (0.60) | ELANE | |
| SCHEMBL7416636 | 0.71 | ELANE (0.75) | ELANE | |
| SCHEMBL7018079 | 0.70 | ELANE (0.66) | ELANE | |
| SCHEMBL7416331 | 0.66 | ELANE (1.00) | ELANE | |
| SCHEMBL8481700 | 0.65 | ELANE (0.49) | ELANE | |
| SCHEMBL7411771 | 0.64 | ELANE (0.67) | ELANE | |
| SCHEMBL7421272 | 0.64 | ELANE (0.63) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0471756-A4 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF | — | 1992-04-08 | — | — | EP | claimed |
| EP-0471756-A1 | SACCHARIN DERIVATIVES USEFUL AS PROTEOLYTIC ENZYME INHIBITORS AND PREPARATION THEREOF. | STERLING WINTHROP INC (US) | 1992-02-26 | — | — | EP | claimed |