Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | LSS | P48449 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | HTR6 | P50406 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7472829 | 0.87 | CMA1 (0.45) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL7461905 | 0.85 | CMA1 (0.39) | SMN1; SMN2LMNATSHRALDH1A1CYP1A2 | |
| SCHEMBL7468000 | 0.83 | CMA1 (0.42) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL8784743 | 0.82 | ALDH3A1 (0.43) | LMNATSHRALDH1A1HTTMAPT | |
| SCHEMBL7471528 | 0.82 | CMA1 (0.40) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| SCHEMBL7468094 | 0.81 | CMA1 (0.41) | LMNAMEN1KMT2ATSHRALDH1A1 | |
| Iodide SCHEMBL7468579 | 0.79 | CMA1 (0.40) | LMNATSHRALDH1A1HTTMAPT | |
| SCHEMBL7462091 | 0.79 | TP53 (0.38) | LMNAMEN1KMT2AHTTMAPT | |
| SCHEMBL7472664 | 0.78 | GAA (0.38) | LMNAMEN1KMT2AMAPT | |
| SCHEMBL7468693 | 0.78 | MAPT (0.37) | SMN1; SMN2LMNAALDH1A1HTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |