Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466539 | 0.92 | BACE1 (0.35) | MAPTSMN1; SMN2BACE1TP53POLB | |
| SCHEMBL7462091 | 0.90 | TP53 (0.38) | MAPTTP53LMNAGAATHRB | |
| SCHEMBL7461905 | 0.83 | CMA1 (0.39) | MAPTSMN1; SMN2ALDH1A1LMNAPSEN1 | |
| SCHEMBL7472829 | 0.83 | CMA1 (0.45) | MAPTALDH1A1LMNAPSEN1PSEN2 | |
| SCHEMBL7472664 | 0.82 | GAA (0.38) | MAPTCA1CA2LMNAPOLB | |
| SCHEMBL8784743 | 0.80 | ALDH3A1 (0.43) | MAPTALDH1A1BACE1LMNAGAA | |
| SCHEMBL7471528 | 0.80 | CMA1 (0.40) | MAPTALDH1A1PSEN1PSEN2APH1B | |
| SCHEMBL7468000 | 0.80 | CMA1 (0.42) | MAPTALDH1A1LMNAPOLBGAA | |
| SCHEMBL7465884 | 0.78 | AKR1C3 (0.38) | MAPTSMN1; SMN2ALDH1A1LMNAHTT | |
| SCHEMBL7468094 | 0.77 | CMA1 (0.41) | MAPTCA2CA9ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |