Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7468000 | 0.96 | CMA1 (0.42) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL8784743 | 0.95 | ALDH3A1 (0.43) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7471528 | 0.94 | CMA1 (0.40) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7468094 | 0.93 | CMA1 (0.41) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7461905 | 0.92 | CMA1 (0.39) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| Iodide SCHEMBL7468579 | 0.91 | CMA1 (0.40) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7460693 | 0.89 | CMA1 (0.40) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7468036 | 0.88 | NOD1 (0.39) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7460295 | 0.87 | CMA1 (0.41) | CMA1ALDH3A1KDM4EALDH1A1HPGD | |
| SCHEMBL7465884 | 0.87 | AKR1C3 (0.38) | ALDH1A1TSHRHTTMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |