Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | FLT3 | P36888 | 2/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.44 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471355 | 0.89 | MAPT (0.43) | HPGDALDH1A1FLT3MAPTMEN1 | |
| SCHEMBL5444081 | 0.86 | HPGD (0.48) | HPGDKDM4EALDH1A1HSD17B10FLT3 | |
| SCHEMBL7473157 | 0.85 | MAPT (0.43) | HPGDALDH1A1FLT3MAPTMEN1 | |
| SCHEMBL8987601 | 0.85 | MMP2 (0.50) | HPGDKDM4EALDH1A1HSD17B10FLT3 | |
| SCHEMBL7465939 | 0.84 | MAPT (0.43) | FLT3MAPTMEN1POLBKMT2A | |
| SCHEMBL7472733 | 0.84 | ALDH1A1 (0.39) | HPGDKDM4EALDH1A1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL7462715 | 0.84 | MAPT (0.42) | KDM4EFLT3MAPTMEN1POLB | |
| SCHEMBL7470341 | 0.84 | MAPT (0.36) | FLT3MAPTMEN1POLBKMT2A | |
| SCHEMBL7477278 | 0.83 | MAPT (0.42) | HPGDALDH1A1MAPTMEN1POLB | |
| Hydrochloric Acid SCHEMBL7471438 | 0.82 | KDM4E (0.45) | HPGDKDM4EALDH1A1HSD17B10FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |