Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22927238 | 1.00 | USP2 (0.39) | USP2ALDH1A1GAAPKMHPGD | |
| SCHEMBL2265274 | 0.82 | ALOX5 (0.31) | ALOX5 | |
| SCHEMBL4407059 | 0.79 | — | — | |
| SCHEMBL7454283 | 0.78 | — | — | |
| SCHEMBL14544792 | 0.77 | ALOX5 (0.43) | ALDH1A1PKMTSHRALOX5NPC1 | |
| Hydrochloric Acid SCHEMBL28936756 | 0.76 | ALOX5 (0.34) | ALDH1A1GAAALOX5 | |
| SCHEMBL19906388 | 0.75 | TSHR (0.36) | TSHRRORCNPC1MAPTNFKB1 | |
| SCHEMBL22295391 | 0.75 | CXCR1 (0.33) | TSHRNPC1MAPTNFKB1RAB9A | |
| SCHEMBL13881107 | 0.75 | TSHR (0.32) | TSHRNPC1MAPTNFKB1RAB9A | |
| SCHEMBL22838600 | 0.72 | KEAP1 (0.44) | ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737682-B1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI CHEMICALS INC (JP) | 2002-01-09 | — | — | EP | disclosed |
| CN-1061657-C | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 2001-02-07 | — | — | CN | disclosed |
| US-5747518-A | EFFECTIVE AGAINST CHEMICAL RESISTANT FUNGI; NONPHYTOTOXIC TO CROPS | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-05-05 | — | — | US | disclosed |
| CN-1146993-A | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS (JP) | 1997-04-09 | — | — | CN | disclosed |
| EP-0737682-A1 | Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1996-10-16 | — | — | EP | disclosed |