SCHEMBL2265274

SCHEMBL2265274

CC(C)CC(C)c1sccc1N

nearest known ligand 0.35

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7465963 0.82 USP2 (0.39) ALOX5
SCHEMBL22927238 0.82 USP2 (0.39) ALOX5
SCHEMBL12229140 0.78 ALOX5 (0.42) ALOX5
SCHEMBL4407059 0.77
SCHEMBL7454283 0.76
SCHEMBL19274403 0.76
SCHEMBL20692523 0.74 PDE7A (0.32) ALOX5
Hydrochloric Acid SCHEMBL28936756 0.74 ALOX5 (0.34) ALOX5
SCHEMBL13155557 0.72 FFAR2 (0.30)
SCHEMBL3789366 0.71 PDE7A (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350293-A Refining method of 3-amino-2- (1, 3-dimethylbutyl) thiophene 辽宁鑫义源锦新材料股份有限公司 2025-01-24 CN claimed
CN-119350293-A Refining method of 3-amino-2- (1, 3-dimethylbutyl) thiophene 辽宁鑫义源锦新材料股份有限公司 2025-01-24 CN disclosed
CN-119350293-A Refining method of 3-amino-2- (1, 3-dimethylbutyl) thiophene 辽宁鑫义源锦新材料股份有限公司 2025-01-24 CN disclosed
CN-119350293-A Refining method of 3-amino-2- (1, 3-dimethylbutyl) thiophene 辽宁鑫义源锦新材料股份有限公司 2025-01-24 CN disclosed
CN-114773327-B Preparation method of penthiopyrad intermediate 广东优康精细化工有限公司 2023-08-18 CN disclosed
EP-3677572-B1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE JAPAN FINECHEM COMPANY INC (JP) 2023-06-07 EP disclosed
CN-114773327-A Preparation method of penthiopyrad intermediate 广东优康精细化工有限公司 2022-07-22 CN disclosed
EP-3677572-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE Japan Finechem Company, Inc. (JP) 2020-07-08 EP disclosed
US-20200181091-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE JAPAN FINECHEM COMPANY, INC. (JP) 2020-06-11 US disclosed
CN-110891940-A Process for preparing pyrazole-4-carboxamide derivatives 日本凡凯姆股份有限公司 2020-03-17 CN disclosed
EP-0737682-B1 Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient MITSUI CHEMICALS INC (JP) 2002-01-09 EP disclosed
US-6331639-B2 BY REACTING A 3-((ALKYL, ALKOXY, PHENYL OR HETEROARYL)CARBONYLAMINO)THIOPHENE WITH A KETONE IN THE PRESENCE OF AN ACID AND REDUCING THE REACTION MIXTURE; AGRICULTURAL FUNGICIDES MITSUI CHEMICALS, INC. (JP) 2001-12-18 US disclosed
US-6331634-B1 FUNGICIDES MITSUI CHEMICALS, INC. (JP) 2001-12-18 US disclosed
US-20010023295-A1 Process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative KATSUTA HIROYUKI (JP) 2001-09-20 US disclosed
US-6239282-B1 ALKYLATING THE CORRESPONDING 3-AMIDOTHIOPHENE COMPOUND MITSUI CHEMICALS, INC. (JP) 2001-05-29 US disclosed
EP-1036793-A2 A process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative Mitsui Chemicals, Inc. (JP) 2000-09-20 EP disclosed
US-5869427-A Substituted thiophene derivative and plant disease control agent comprising the same as active ingredient MITSUI CHEMICALS, INC. (JP) 1999-02-09 US disclosed
EP-0841336-A1 Substituted thiopene derivative and plant disease control agent comprising the same as active ingredient MITSUI TOATSU CHEMICALS, Inc. (JP) 1998-05-13 EP disclosed
US-5747518-A EFFECTIVE AGAINST CHEMICAL RESISTANT FUNGI; NONPHYTOTOXIC TO CROPS MITSUI TOATSU CHEMICALS, INC. (JP) 1998-05-05 US disclosed
EP-0737682-A1 Substituted thiophene derivative and agricultural and horticultural fungicide containing the same as active ingredient MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1996-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010023295-A1 Process for preparing 2-alkyl-3-aminothiophene derivative and 3-aminothiophene derivative SULT1E1, CYP4B1, CYP3A4 ALOX5 1596/4885
US-20200181091-A1 PRODUCTION METHOD FOR PYRAZOLE-4-CARBOXAMIDE DERIVATIVE AADAC, CYP3A4, ABAT ALOX5 933/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.