Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465984 | 1.00 | ALDH1A1 (0.43) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL7465971 | 0.90 | RAB9A (0.41) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL28102381 | 0.85 | ALDH1A1 (0.46) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL32662599 | 0.84 | CYP1A2 (0.46) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL16425424 | 0.82 | TDP1 (0.55) | ALDH1A1CYP1A2MAPTHPGDMEN1 | |
| SCHEMBL20299855 | 0.82 | BCL9 (0.44) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL8135055 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL8135051 | 0.82 | ALDH1A1 (0.41) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL2995979 | 0.81 | CYP1A2 (0.44) | ALDH1A1CYP1A2PTGDR2MAPTHPGD | |
| SCHEMBL2993625 | 0.81 | CYP1A2 (0.44) | ALDH1A1CYP1A2PTGDR2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022277-B1 | NEW TAXANE DERIVATIVES | YAKULT HONSHA KK (JP) | 2002-12-04 | — | — | EP | disclosed |
| CN-1062561-C | 7-halo-and 7 beta, 8 beta-methylene-paclitaxel, antitumor use and pharmaceutical composition containing the same | PHARMAIN & UPJOHN CO (US) | 2001-02-28 | — | — | CN | disclosed |
| US-6136808-A | ANTITUMOR AGENTS FROM PLANTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1022277-A1 | NEW TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-07-26 | — | — | EP | disclosed |
| CN-1261072-A | 7-halogenated and 7 beta, 8 beta-methylene-taxinol, its usage against cancers and medicinal compositions containing it | UPJOHN CO (US) | 2000-07-26 | — | — | CN | disclosed |
| CN-1095377-A | 7-halo-and 7 beta, 8 beta-methylene-paclitaxel, antitumor use and pharmaceutical composition containing the same | UPJOHN CO (US) | 1994-11-23 | — | — | CN | disclosed |