Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.39 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.39 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465984 | 0.90 | ALDH1A1 (0.43) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL7465976 | 0.90 | ALDH1A1 (0.43) | MEN1KMT2ATDP1ALDH1A1LMNA | |
| SCHEMBL5492543 | 0.85 | ALDH1A1 (0.46) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL16425424 | 0.84 | TDP1 (0.55) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL20299852 | 0.81 | BCL9 (0.46) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL2993623 | 0.81 | RAB9A (0.47) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL2995971 | 0.81 | CYP1A2 (0.42) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL7518128 | 0.79 | SMN1; SMN2 (0.49) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL8489170 | 0.78 | CYP1A2 (0.40) | RAB9AMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL2153548 | 0.78 | HTT (0.51) | RAB9AMEN1KMT2ATDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1022277-B1 | NEW TAXANE DERIVATIVES | YAKULT HONSHA KK (JP) | 2002-12-04 | — | — | EP | disclosed |
| US-6136808-A | ANTITUMOR AGENTS FROM PLANTS | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2000-10-24 | — | — | US | disclosed |
| EP-1022277-A1 | NEW TAXANE DERIVATIVES | Kabushiki Kaisha Yakult Honsha (JP) | 2000-07-26 | — | — | EP | disclosed |