SCHEMBL7465987

SCHEMBL7465987

COC(=O)c1cccc(C(F)(F)F)c1.O=S(=O)(O)Cl

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.55
CES2 O00748 1/20 0.54
MRGPRX4 Q96LA9 1/20 0.53
CACNA1B Q00975 1/20 0.53
SDHB P21912 1/20 0.51
RORC P51449 1/20 0.50
NOTUM Q6P988 1/20 0.50
POLB P06746 3/20 0.49
ALDH1A1 P00352 2/20 0.49
KAT6A Q92794 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
LMNA P02545 2/20 0.48
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48
CA2 P00918 1/20 0.48
CA9 Q16790 1/20 0.48
P2RX1 P51575 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27403082 0.95 NPSR1 (0.56) NPSR1CES2MRGPRX4CACNA1BSDHB
SCHEMBL31355711 0.91 CES2 (0.65) NPSR1CES2MRGPRX4CACNA1BNOTUM
SCHEMBL40351 0.91 CES2 (0.65) NPSR1CES2MRGPRX4CACNA1BNOTUM
Ethane SCHEMBL27386119 0.89 CES2 (0.62) NPSR1CES2MRGPRX4CACNA1BNOTUM
SCHEMBL22498190 0.86 CACNA1B (0.56) NPSR1CES2MRGPRX4CACNA1BSDHB
SCHEMBL29528521 0.86 CACNA1B (0.56) NPSR1CES2MRGPRX4CACNA1BSDHB
SCHEMBL7471216 0.86 MAPT (0.54) NPSR1CES2POLBALDH1A1MEN1
Butane SCHEMBL27366277 0.85 ALDH1A1 (0.62) NPSR1CES2MRGPRX4RORCNOTUM
SCHEMBL7471082 0.85 NPSR1 (0.55) NPSR1CES2KAT6AMEN1KMT2A
SCHEMBL7474311 0.83 LMNA (0.51) NPSR1CES2POLBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0859774-B1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 2002-04-03 EP disclosed
EP-0859774-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AG (DE) 1998-08-26 EP disclosed
WO-1997016449-A1 SUBSTITUTED SULPHONYLAMINO (THIO)CARBONYL COMPOUNDS AS HERBICIDES BAYER AKTIENGESELLSCHAFT (DE) 1997-05-09 WO disclosed