Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.54 |
| ▸ | TDO2 | P48775 | 4/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466004 | 0.86 | IDO1 (0.40) | IDO1TDO2SLC6A4 | |
| SCHEMBL7471512 | 0.85 | SRD5A2 (0.36) | IDO1TDO2SLC6A4KDM4E | |
| SCHEMBL7462087 | 0.82 | IDO1 (0.36) | IDO1TDO2KDM4E | |
| SCHEMBL7465983 | 0.81 | IDO1 (0.57) | IDO1TDO2SLC6A4 | |
| SCHEMBL7533169 | 0.78 | MGLL (0.38) | SLC6A4 | |
| SCHEMBL7460305 | 0.77 | IDO1 (0.53) | IDO1TDO2SLC6A4 | |
| SCHEMBL7464307 | 0.77 | IDO1 (0.55) | IDO1TDO2SLC6A4CNR2 | |
| SCHEMBL7466815 | 0.76 | MEN1 (0.37) | IDO1TDO2SLC6A4KDM4E | |
| SCHEMBL7461974 | 0.76 | IDO1 (0.51) | IDO1TDO2SLC6A4 | |
| SCHEMBL7471840 | 0.76 | ACP3 (0.42) | IDO1TDO2SLC6A4KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |