Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP3 | P15309 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | TDO2 | P48775 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | KCNK2 | O95069 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7465983 | 0.87 | IDO1 (0.57) | ACP3IDO1TDO2SLC6A4SLC6A2 | |
| SCHEMBL7471512 | 0.85 | SRD5A2 (0.36) | IDO1TDO2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7466004 | 0.83 | IDO1 (0.40) | IDO1TDO2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7461974 | 0.80 | IDO1 (0.51) | IDO1TDO2SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL7466815 | 0.80 | MEN1 (0.37) | IDO1TDO2SLC6A4SLC6A3TSHR | |
| SCHEMBL7464863 | 0.79 | IDO1 (0.45) | ACP3IDO1TDO2SLC6A4CACNA1C | |
| SCHEMBL7468229 | 0.77 | ACP3 (0.44) | ACP3ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL7462989 | 0.76 | IDO1 (0.54) | IDO1TDO2SLC6A4KDM4E | |
| SCHEMBL7466003 | 0.76 | OPRD1 (0.39) | TSHRMEN1KMT2AOPRM1OPRK1 | |
| SCHEMBL11054725 | 0.75 | ACP3 (0.53) | ACP3IDO1TDO2SLC6A4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |