Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.51 |
| ▸ | RARA | P10276 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | PIM1 | P11309 | 2/20 | 0.48 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.47 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.47 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11457413 | 0.90 | PIM1 (0.54) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL7467756 | 0.87 | RARB (0.49) | RARBTP53TSHRMEN1KMT2A | |
| SCHEMBL9990974 | 0.86 | PIM1 (0.58) | TP53MEN1KMT2APIM1LMNA | |
| SCHEMBL7461350 | 0.84 | RARB (0.58) | RARBTP53RARAMEN1KMT2A | |
| SCHEMBL11455911 | 0.83 | MAOA (0.62) | RARBTP53TSHRPLA2G4BMEN1 | |
| SCHEMBL18591899 | 0.81 | PIM1 (0.58) | TP53MEN1KMT2APIM1PIM2 | |
| SCHEMBL11455696 | 0.79 | MEN1 (0.48) | TP53TSHRMEN1KMT2ATDP1 | |
| SCHEMBL11279691 | 0.78 | CA12 (0.61) | TP53TSHRMEN1KMT2ATDP1 | |
| SCHEMBL11464989 | 0.77 | FLT3 (0.63) | TP53TDP1NR1H4PIM1PIM2 | |
| SCHEMBL7556985 | 0.77 | MAPT (0.48) | RARBRARAMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214306-A1 | LIQUID CRYSTAL COMPOUNDS | Qinetiq Limited (GB) | 2002-06-19 | — | — | EP | disclosed |
| WO-2001021606-A1 | LIQUID CRYSTAL COMPOUNDS | QINETIQ LIMITED (GB) | 2001-03-29 | — | — | WO | disclosed |