Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.44 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474692 | 0.89 | AGTR1 (0.43) | AGTR1AGTR2ADAM17 | |
| SCHEMBL6635318 | 0.85 | AGTR1 (0.54) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7840690 | 0.84 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7579266 | 0.79 | MAPT (0.47) | AGTR1AGTR2ADAM17 | |
| Hydrochloric Acid SCHEMBL9181040 | 0.76 | AGTR1 (0.45) | AGTR1AGTR2KDM4E | |
| SCHEMBL2142522 | 0.76 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL29681307 | 0.76 | AGTR1 (0.70) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9180925 | 0.76 | ADAM17 (0.40) | AGTR1AGTR2ADAM17 | |
| SCHEMBL9597785 | 0.76 | MAP2K4 (0.34) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL4126842 | 0.75 | AGTR1 (0.69) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |