Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 2/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.43 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466358 | 0.89 | AGTR1 (0.44) | AGTR1AGTR2ADAM17 | |
| SCHEMBL6635318 | 0.87 | AGTR1 (0.54) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL7840690 | 0.86 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL7471684 | 0.78 | MAPT (0.44) | AGTR1AGTR2ADAM17 | |
| Hydrochloric Acid SCHEMBL9181040 | 0.78 | AGTR1 (0.45) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9180925 | 0.77 | ADAM17 (0.40) | AGTR1AGTR2ADAM17 | |
| Hydrochloric Acid SCHEMBL9378493 | 0.76 | AGTR1 (0.44) | AGTR1AGTR2 | |
| Hydrochloric Acid SCHEMBL9178269 | 0.76 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL2142522 | 0.76 | AGTR1 (0.70) | AGTR1AGTR2 | |
| SCHEMBL29681307 | 0.76 | AGTR1 (0.70) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016071-A1 | HETEROCYCLIC DERIVATIVES AS ANGIOTENSIN II ANTAGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-08-19 | — | — | WO | disclosed |