Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.72 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.40 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.40 |
| ▸ | NOD1 | Q9Y239 | 2/20 | 0.40 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.38 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.38 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470471 | 0.84 | CMA1 (0.80) | CMA1CA12CA9LMNAALDH1A1 | |
| SCHEMBL7463672 | 0.84 | CMA1 (1.00) | CMA1FEN1CA12CA9 | |
| SCHEMBL7467460 | 0.84 | CMA1 (0.75) | CMA1ALDH3A1NOD2NOD1CXCL8 | |
| SCHEMBL7469021 | 0.83 | CMA1 (0.74) | CMA1ALDH3A1CA12CA9ALDH1A1 | |
| SCHEMBL7464965 | 0.82 | CMA1 (0.85) | CMA1FEN1CA12CA9LMNA | |
| SCHEMBL7460050 | 0.80 | CMA1 (0.69) | CMA1CA12CA9LMNAKDM4E | |
| SCHEMBL7460816 | 0.80 | CMA1 (0.68) | CMA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL7466403 | 0.80 | CMA1 (0.81) | CMA1FEN1CA12CA9HTR6 | |
| SCHEMBL7461813 | 0.80 | CMA1 (0.68) | CMA1FEN1CA12CA9HTR6 | |
| SCHEMBL7472683 | 0.80 | CMA1 (0.81) | CMA1FEN1CA12CA9KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |