Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 1/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | FEN1 | P39748 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | RNASEH1 | O60930 | 1/20 | 0.46 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.46 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6980480 | 0.88 | CMA1 (0.57) | CMA1KDM4EGAAALDH1A1ADORA3 | |
| SCHEMBL7470471 | 0.86 | CMA1 (0.80) | CMA1ALDH1A1CA12CA9PTGS2 | |
| SCHEMBL7463672 | 0.86 | CMA1 (1.00) | CMA1FEN1CA12CA9SMN1; SMN2 | |
| SCHEMBL7466485 | 0.84 | CMA1 (0.72) | CMA1KDM4EHTTALDH1A1ADORA3 | |
| SCHEMBL7464965 | 0.83 | CMA1 (0.85) | CMA1KDM4EHTTGAAALDH1A1 | |
| SCHEMBL7461813 | 0.81 | CMA1 (0.68) | CMA1GAAFEN1CA12CA9 | |
| SCHEMBL7460816 | 0.81 | CMA1 (0.68) | CMA1KDM4EGAAALDH1A1CA12 | |
| SCHEMBL7472683 | 0.81 | CMA1 (0.81) | CMA1KDM4EHTTGAAALDH1A1 | |
| SCHEMBL7466403 | 0.81 | CMA1 (0.81) | CMA1FEN1CA12CA9HTR6 | |
| SCHEMBL7469021 | 0.80 | CMA1 (0.74) | CMA1ALDH1A1CA12CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0795548-B1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-5814631-A | CHYMASE INHIBITOR, CARDIVASCULAR | SUNTORY LIMITED (JP) | 1998-09-29 | — | — | US | disclosed |
| EP-0795548-A1 | QUINAZOLINE DERIVATIVES AND USE THEREOF | SUNTORY LIMITED (JP) | 1997-09-17 | — | — | EP | disclosed |