Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 2/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HBB | P68871 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5058946 | 0.91 | KMT2A (0.54) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL16746567 | 0.89 | CA2 (0.43) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL16983221 | 0.85 | KMT2A (0.43) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL63804 | 0.85 | ALDH1A1 (0.52) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL8038944 | 0.84 | ALDH1A1 (0.50) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL8039657 | 0.82 | ALDH1A1 (0.54) | MAPTKMT2AALDH1A1MEN1GAA | |
| Hydrochloric Acid SCHEMBL8040784 | 0.82 | KMT2A (0.49) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL7468442 | 0.82 | CYP2A6 (0.42) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL8028832 | 0.82 | KMT2A (0.42) | MAPTKMT2AALDH1A1MEN1GAA | |
| SCHEMBL10189317 | 0.81 | ALDH1A1 (0.41) | MAPTKMT2AALDH1A1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711768-B1 | BENZIMIDAZOLE DERIVATIVE | MITSUI CHEMICALS INC (JP) | 2002-02-13 | — | — | EP | disclosed |
| EP-0711768-A1 | BENZIMIDAZOLE DERIVATIVE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1996-05-15 | — | — | EP | disclosed |