Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.57 |
| ▸ | TDO2 | P48775 | 3/20 | 0.57 |
| ▸ | ACP3 | P15309 | 3/20 | 0.43 |
| ▸ | PNMT | P11086 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7471840 | 0.87 | ACP3 (0.42) | IDO1TDO2ACP3LMNATP53 | |
| SCHEMBL7471512 | 0.82 | SRD5A2 (0.36) | IDO1TDO2LMNAHTTSMN1; SMN2 | |
| SCHEMBL7462989 | 0.81 | IDO1 (0.54) | IDO1TDO2SLC6A4 | |
| SCHEMBL7462087 | 0.78 | IDO1 (0.36) | IDO1TDO2LMNAMAPTGAA | |
| SCHEMBL7466004 | 0.76 | IDO1 (0.40) | IDO1TDO2SLC6A2SLC6A4 | |
| SCHEMBL7464863 | 0.76 | IDO1 (0.45) | IDO1TDO2ACP3OPRM1OPRD1 | |
| SCHEMBL7466690 | 0.76 | IDO1 (0.55) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL7533169 | 0.75 | MGLL (0.38) | MAPTS1PR3SLC6A2SLC6A4 | |
| SCHEMBL9116195 | 0.74 | TACR1 (0.47) | IDO1TDO2 | |
| SCHEMBL7466815 | 0.73 | MEN1 (0.37) | IDO1TDO2LMNASMN1; SMN2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |