Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.51 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466776 | 0.85 | GSTP1 (0.42) | MAOBSQORRAB9ASMN1; SMN2GAA | |
| SCHEMBL7460079 | 0.82 | RXRA (0.40) | MAOBFFAR1GSTP1GABRG2GABRB3 | |
| SCHEMBL7455789 | 0.82 | RXRA (0.43) | MAOBFFAR1SMN1; SMN2GSTP1L3MBTL1 | |
| SCHEMBL7461463 | 0.80 | ABCB1 (0.44) | MAOBFFAR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7468369 | 0.79 | IKBKB (0.48) | NPC1SMN1; SMN2GSTP1GABRG2GABRB3 | |
| SCHEMBL7466725 | 0.78 | RXRA (0.44) | MAOBFFAR1PTGDR2RXRARXRB | |
| SCHEMBL4280169 | 0.74 | PTGER1 (0.43) | NPC1RAB9ASMN1; SMN2KDM4EMAPK1 | |
| SCHEMBL1119492 | 0.74 | RAB9A (0.46) | MAOBNPC1RAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL9035933 | 0.74 | MAOB (0.56) | MAOBNPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL20240306 | 0.73 | MAOB (0.80) | MAOBFFAR1AKR1B1RAB9AGSTP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1244617-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | Ortho-McNeil Pharmaceutical, Inc. (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047875-A1 | SUBSTITUTED AMINOALKYLAMIDE DERIVATIVES AS ANTAGONISTS OF FOLLICLE STIMULATING HORMONE | ORTHO-MCNEIL PHARMACEUTICAL, INC. (US) | 2001-07-05 | — | — | WO | claimed |