Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.53 |
| ▸ | PNMT | P11086 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AOC1 | P19801 | 2/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | BPTF | Q12830 | 1/20 | 0.33 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.33 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TOP2A | P11388 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7466628 | 0.83 | CSNK2A1 (0.42) | CSNK2A1MEN1LMNAKMT2ARORC | |
| SCHEMBL6490259 | 0.76 | CSNK2A1 (0.56) | CSNK2A1NOS3NOS1MEN1LMNA | |
| SCHEMBL855754 | 0.75 | IRAK4 (0.47) | CSNK2A1PNMTNOS3NOS1IRAK4 | |
| SCHEMBL29786441 | 0.75 | IRAK4 (0.47) | CSNK2A1PNMTNOS3NOS1IRAK4 | |
| SCHEMBL7468868 | 0.74 | CSNK2A1 (0.36) | CSNK2A1MEN1LMNAKMT2ARORC | |
| SCHEMBL30139653 | 0.72 | CSNK2A1 (0.59) | CSNK2A1PNMTNOS3NOS1MEN1 | |
| SCHEMBL12697235 | 0.70 | NOS3 (0.50) | CSNK2A1NOS3NOS1LMNAPOLB | |
| SCHEMBL2452287 | 0.70 | PNMT (0.36) | PNMTBPTFKAT2BPDCD1LG2CD274 | |
| SCHEMBL4390974 | 0.69 | CSNK2A1 (0.47) | CSNK2A1NOS3NOS1IRAK4 | |
| SCHEMBL16954261 | 0.69 | ADRB3 (0.39) | CSNK2A1MEN1LMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0891336-B1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AG (DE) | 2002-06-05 | — | — | EP | disclosed |
| EP-0891336-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1999-01-20 | — | — | EP | disclosed |
| WO-1997035845-A1 | SUBSTITUTED 1-METHYL-3-BENZYLURACILS | BASF AKTIENGESELLSCHAFT (DE) | 1997-10-02 | — | — | WO | disclosed |