Methacrylic Acid

Methacrylic Acid

SCHEMBL7466787

C=C(C)C(=O)O.CCC(CO)(CO)COC(=O)O

nearest known ligand 0.39

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPK1 P28482 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HIF1A Q16665 1/20 0.39
THRB P10828 2/20 0.33
TSHR P16473 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL8571034 0.91 ALDH1A1 (0.42) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL1357290 0.89 MAPK1 (0.42) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Bicarbonate SCHEMBL10991903 0.87 MAPK1 (0.41) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL4886913 0.86 THRB (0.40) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL16653852 0.85 THRB (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL1673561 0.85 THRB (0.39) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL9008772 0.85 MAPK1 (0.42) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Propene SCHEMBL23036014 0.84 ALDH1A1 (0.48) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL10790154 0.83 THRB (0.40) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Methacrylic Acid SCHEMBL8749522 0.83 THRB (0.40) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0909237-B1 ABSORBENT INSERTS, METHOD OF PRODUCING THEM AND THEIR USE STOCKHAUSEN CHEM FAB GMBH (DE) 2002-06-12 EP claimed
EP-0862590-B1 FLUID-ABSORBING POLYMERS, PROCESS FOR THE PREPARATION AND USE THEREOF STOCKHAUSEN CHEM FAB GMBH (DE) 1999-08-18 EP claimed
US-5837789-A SUPERABSORBENT, CROSSLINKED; SANITARY NAPKINS, DIAPERS, CABLES STOCKHAUSEN GMBH & CO. KG (DE) 1998-11-17 US claimed
EP-0862590-A1 FLUID-ABSORBING POLYMERS, PROCESS FOR THE PREPARATION AND USE THEREOF STOCKHAUSEN GmbH & CO. KG (DE) 1998-09-09 EP claimed
WO-1997019116-A1 FLUID-ABSORBING POLYMERS, PROCESS FOR THE PREPARATION AND USE THEREOF STOCKHAUSEN GMBH & CO. KG (DE) 1997-05-29 WO claimed