Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 4/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | CTSK | P43235 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 2/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7462325 | 1.00 | CTSS (0.47) | CTSSCTSLCTSKNPC1MAPT | |
| SCHEMBL7466885 | 0.87 | CTNNB1 (0.47) | CTSSCTSLCTSKNPC1MAPT | |
| SCHEMBL7472944 | 0.87 | ALDH1A1 (0.43) | NPC1MAPTRAB9AKMT2APTGFR | |
| SCHEMBL7472858 | 0.87 | ALDH1A1 (0.43) | NPC1MAPTRAB9AKMT2APTGFR | |
| SCHEMBL7462101 | 0.85 | MMP2 (0.47) | NPC1MAPTRAB9AKMT2APTGFR | |
| SCHEMBL7466668 | 0.85 | MMP2 (0.47) | NPC1MAPTRAB9AKMT2APTGFR | |
| SCHEMBL7461667 | 0.84 | ALDH1A1 (0.49) | NPC1MAPTRAB9AKMT2APTGFR | |
| SCHEMBL7463409 | 0.83 | PTGFR (0.44) | NPC1MAPTKDM4ERAB9AKMT2A | |
| SCHEMBL7462284 | 0.82 | ALDH1A1 (0.46) | MAPTRAB9AKMT2APTGFRLMNA | |
| SCHEMBL7469939 | 0.82 | ALDH1A1 (0.46) | MAPTRAB9AKMT2APTGFRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805796-B1 | CELL ADHESION INHIBITORS | BIOGEN INC (US) | 2002-12-11 | — | — | EP | claimed |