Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 11/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8742909 | 0.96 | PTPN11 (0.35) | PTPN11TP53LMNAMAPTTSHR | |
| SCHEMBL7466247 | 0.94 | PTPN11 (0.39) | PTPN11TP53LMNAMAPTUSP2 | |
| SCHEMBL7477081 | 0.90 | GPR119 (0.49) | USP2ALDH1A1TSHR | |
| SCHEMBL7467895 | 0.86 | PTPN11 (0.41) | PTPN11 | |
| SCHEMBL7466948 | 0.85 | NPSR1 (0.36) | TP53LMNAMAPT | |
| SCHEMBL9220084 | 0.84 | POLB (0.34) | TP53LMNAMAPTTSHRPOLB | |
| Trifluoroacetic Acid SCHEMBL8590187 | 0.83 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL7470458 | 0.81 | PTPN11 (0.40) | PTPN11LMNAMAPTUSP2ALDH1A1 | |
| SCHEMBL7469139 | 0.81 | PTPN11 (0.39) | PTPN11USP2ALDH1A1TSHRPOLB | |
| Trifluoroacetic Acid SCHEMBL8742747 | 0.79 | PTPN11 (0.37) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |