Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 11/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7469139 | 0.89 | PTPN11 (0.39) | PTPN11USP2ALDH1A1TSHRPOLB | |
| Trifluoroacetic Acid SCHEMBL8742747 | 0.85 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL7467895 | 0.83 | PTPN11 (0.41) | PTPN11 | |
| Water SCHEMBL8742754 | 0.83 | PTPN11 (0.36) | PTPN11USP2ALDH1A1TSHRMAPT | |
| SCHEMBL7466247 | 0.82 | PTPN11 (0.39) | PTPN11USP2ALDH1A1TSHRMAPT | |
| SCHEMBL7466955 | 0.81 | PTPN11 (0.37) | PTPN11USP2ALDH1A1TSHRMAPT | |
| Trifluoroacetic Acid SCHEMBL8590187 | 0.80 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL7477081 | 0.79 | GPR119 (0.49) | USP2ALDH1A1TSHR | |
| Trifluoroacetic Acid SCHEMBL8742909 | 0.78 | PTPN11 (0.35) | PTPN11TSHRMAPTLMNAPOLB | |
| SCHEMBL7472874 | 0.76 | PTPN11 (0.38) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| US-5773612-A | VASOPRESSIN OR OXYTOCIN RECEPTORS | SANOFI (FR) | 1998-06-30 | — | — | US | disclosed |
| US-5594023-A | 1,3-dihydroindol-2-one derivatives substituted in the 3-position by a nitrogen-containing group, their preparation and the pharmaceutical compositions in which they are present | SANOFI (FR) | 1997-01-14 | — | — | US | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |