Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 18/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL8590187 | 0.96 | PTPN11 (0.39) | PTPN11ADRB2ADRB1ADRB3 | |
| SCHEMBL7466955 | 0.86 | PTPN11 (0.37) | PTPN11 | |
| SCHEMBL7466247 | 0.84 | PTPN11 (0.39) | PTPN11 | |
| SCHEMBL7471274 | 0.83 | NPSR1 (0.38) | PTPN11 | |
| SCHEMBL7470458 | 0.83 | PTPN11 (0.40) | PTPN11 | |
| SCHEMBL7477081 | 0.83 | GPR119 (0.49) | — | |
| SCHEMBL7469139 | 0.83 | PTPN11 (0.39) | PTPN11ADRB2ADRB1ADRB3 | |
| SCHEMBL7477246 | 0.83 | NPSR1 (0.39) | PTPN11 | |
| Trifluoroacetic Acid SCHEMBL8742909 | 0.82 | PTPN11 (0.35) | PTPN11 | |
| SCHEMBL7473790 | 0.81 | LMNA (0.46) | PTPN11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0687251-B1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI SYNTHELABO (FR) | 2002-02-27 | — | — | EP | disclosed |
| WO-1995018105-A1 | 1,3-DIHYDROINDOL-2-ONE DERIVATIVES SUBSTITUTED IN POSITION 3 BY A NITROGEN GROUP AS VASOPRESSIN AND/OR OCYTOCINE AGONISTS AND/OR ANTAGONISTS | SANOFI (FR) | 1995-07-06 | — | — | WO | disclosed |